The most recent edition of Inscriptions features prominently a new essay by Pedro José Grande Sánchez on the topic of Michel Henry’s critique of technology. To Henry our age of scientific-technological domination has produced for us a world in which an objective and homogenising conception of the world has severed our connection to the world of the spirit. In the editorial we bring Henry’s notion of a ‘disease of life’ together with Wolfgang Schirmacher’s ‘death technology’, discussing whether what lies at the core of both these approaches is a common critique of instrumental reason. Read the full editorial in the latest issue of Inscriptions (open access).